Excretion of Cholera Toxin From Escherichia Coli • A Potential Oral Vaccine For Cholera
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Excretion of Cholera Toxin From Escherichia Coli •
A Potential Oral Vaccine For Cholera
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| Creator |
Dasgupta, Ujjala
Guhathakurta, Indrajit Das, Jyotirmoy |
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| Subject |
Molecular & Human Genetics
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| Description |
E~cherichia ooli strain N100 has been mutagenized by transposon mutagenesis
and mutants with a cell surface leaky phenotype have been isolated. The mutant
designated as E. coli N100::Tn5 excreted periplasmic proteins like ribonuclease
and alkaline phosphatase. When this mutant strain was transformed with
plasmids containing cloned cholera toxin genes, the toxin protein synthesized
in the cells were excreted. The potentiality of this strain as a live oral
vaccine for cholera has been discussed.
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| Publisher |
Elsevier
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| Date |
1988
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1441/1/BIOCHEMICAL_AND_BIOPHYSICAL_RESEARCH_COMMUNICATIONS__Volume_153___Issue_3___Pages_967%2D972%2C1988[34].pdf
Dasgupta, Ujjala and Guhathakurta, Indrajit and Das, Jyotirmoy (1988) Excretion of Cholera Toxin From Escherichia Coli • A Potential Oral Vaccine For Cholera. Biochemical and Biophysical Research Communications, 153 (3). pp. 967-972. |
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| Relation |
http://dx.doi.org/10.1016/S0006-291X(88)81322-6
http://www.eprints.iicb.res.in/1441/ |
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