Renal Handling of Amino Acid 99mTechnetium Chelates
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Renal Handling of Amino Acid 99mTechnetium Chelates
|
|
| Creator |
Chattopadhyay, Munna
Banerjee, Somenath |
|
| Subject |
Drug Development/Diagnostics & Biotechnology
|
|
| Description |
Four amino acids-alanine, 2,3diaminopropionic acid, cystine, and cystein-and also one diamine,
ethylenediamine, were chelated with 99m-technetium FTC), and their renal excretion patterns were
studied in rabbits in the presence and absence of two renal tubular transport inhibitors, probenecid and
2,4dinitrophenol. From the depression of renal excretion for the first three amino acid chelates, in the
presence of the inhibitors, a renal tubular excretory pathway of elimination was suggested for these
compounds. The renal excretions of 99mTc-cystein and 99”Tc-ethylenediamine however, remained
undepressed under similar experimental conditions. An explanation of these observations was forwarded
from the possible chemical structures of these chelates
|
|
| Publisher |
Elsevier
|
|
| Date |
1988
|
|
| Type |
Article
PeerReviewed |
|
| Format |
application/pdf
|
|
| Identifier |
http://www.eprints.iicb.res.in/1455/1/JOURNAL_OF_INORGANIC_BIOCHEMISTRY__Volume_34___Issue_1___Pages_25%2D40%2C1988[26].pdf
Chattopadhyay, Munna and Banerjee, Somenath (1988) Renal Handling of Amino Acid 99mTechnetium Chelates. Journal of Inorganic Biochemistry, 34 (1). pp. 25-40. |
|
| Relation |
http://dx.doi.org/10.1016/0162-0134(88)85015-3
http://www.eprints.iicb.res.in/1455/ |
|