Synthesis of Medium Ring Azaheterocycles and Analogues from Carbohydrate Derivatives
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Synthesis of Medium Ring Azaheterocycles and Analogues
from Carbohydrate Derivatives
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| Creator |
Das Adhikary, Nirmal
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| Subject |
Chemistry
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| Description |
The remarkable flowering of organometallic chemistry, notably of the transition metals, during the second half of the 20th century, has enriched and transformed chemical science to a degree and in ways that have few parallels in the history of the discipline. Of all organometallic chemistry known, palladium catalysis has achieved the status of an indispensable tool for both common and state-of-the-art organic synthesis. Palladiumcatalysed
cross-coupling to form C–C bonds is one of the most frequently used catalytic processes for synthesizing medicinally active compounds. Examples of products prepared by this method are the antihypertensive drugs known as sartans1, the anti-asthma drug Singulair (montelukast sodium), products such as sunscreen2 and the polymers used for light-emitting diodes and for sensing the explosive trinitrotoluene (TNT)3–6. The intermediates that form the
new C–C bond in the final product are classic organometallic species.
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| Date |
2011-08
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| Type |
Thesis
NonPeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1471/1/Thesis_.pdf
Das Adhikary, Nirmal (2011) Synthesis of Medium Ring Azaheterocycles and Analogues from Carbohydrate Derivatives. PhD thesis, Jadavpur University. |
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| Relation |
http://www.eprints.iicb.res.in/1471/
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