Effect of alpha-naphthylthiourea on (Na+ + K+)-ATPases in albino rats.
IR@CFTRI: CSIR-Central Food Technological Research Institute, Mysore
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http://ir.cftri.com/8627/
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| Title |
Effect of alpha-naphthylthiourea on (Na+ + K+)-ATPases in albino rats.
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| Creator |
Patil, T. N.
Radhakrishnamurty, R. |
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| Subject |
26 Pesticide Chemistry
17 Toxicology |
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| Description |
PESTAB. A study was undertaken to determine the effects of alpha-naphthylthiourea (ANTU), a specific acute rodenticide, on ATPases in different tissues. Female Wistar rats were given oral doses of ANTU (10 mg/kg). Erythrocyte membrane, liver microsomes, and kidney microsomes were assayed for (Na+ + K+)-ATPases. Inhibition of (Na+ + K+)-ATPases occurred in erythrocyte membranes and kidney microsomes. There were no effects observed with ATPases activated by 2,4-dinitrophenol, magnesium or calcium from liver and kidney mitochondria. There was substantial reversal of inhibition by phosphatidyl choline, phosphatidyl ethanolamine, and adenosine triphosphate.
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| Date |
1978
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Language |
en
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| Rights |
—
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| Identifier |
http://ir.cftri.com/8627/1/Indian%20Journal%20of%20Biochemistry%20and%20Biophysics%2C%20Volume-15%28%20%281978%29%20294-298.pdf
Patil, T. N. and Radhakrishnamurty, R. (1978) Effect of alpha-naphthylthiourea on (Na+ + K+)-ATPases in albino rats. Indian Journal of Biochemistry and Biophysics, 15 (4). 294-298; 29 ref.. |
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