Antimicrobial, antioxidant, cytotoxicity and platelet aggregation inhibitory activity of a novel molecule isolated and characterized from mango ginger (Curcuma amada Roxb.) rhizome
IR@CFTRI: CSIR-Central Food Technological Research Institute, Mysore
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Relation |
http://ir.cftri.com/9813/
JOB-01-10 |
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Title |
Antimicrobial, antioxidant, cytotoxicity and platelet aggregation
inhibitory activity of a novel molecule isolated and characterized from
mango ginger (Curcuma amada Roxb.) rhizome
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Creator |
Policegoudra, R. S.
Rehna, K. Jaganmohan Rao, L. Aradhya, S. M. |
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Subject |
30 Spices/Condiments
32 Antioxidants |
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Description |
Mango ginger (Curcuma amada Roxb.) rhizome is used in the manufacture of pickles and other food preparations
due to its unique raw mango fl avour. The chloroform extract of mango ginger rhizome was subjected to antibacterial
activity-guided purifi cation by repeated silica gel column chromatography to obtain a pure compound. The structure
of the isolated compound was deduced by analysing UV, IR, LC-MS and 2D-HMQCT NMR spectral data, and named
it as amadaldehyde, a novel compound. It exhibited a wide range of antibacterial activity with potential bactericidal
activity against several bacteria. The purifi ed compound also exhibited antioxidant activity, cytotoxicity and platelet
aggregation inhibitory activities.
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Date |
2010
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Language |
en
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Rights |
—
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Identifier |
http://ir.cftri.com/9813/1/J._Biosci._35%282%29%2C_June_2010%2C_231%E2%80%93240.pdf
Policegoudra, R. S. and Rehna, K. and Jaganmohan Rao, L. and Aradhya, S. M. (2010) Antimicrobial, antioxidant, cytotoxicity and platelet aggregation inhibitory activity of a novel molecule isolated and characterized from mango ginger (Curcuma amada Roxb.) rhizome. Journal of Biosciences, 35 (2). 231-240. |
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