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Prenatal toxicity of heptachlor in albino rats.

IR@CFTRI: CSIR-Central Food Technological Research Institute, Mysore

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Relation http://ir.cftri.com/2258/
 
Title Prenatal toxicity of heptachlor in albino rats.
 
Creator Rani, B. E. A.
Krishnakumari, M. K.
 
Subject 26 Pesticide Chemistry
17 Toxicology
 
Description Exposure of the cyclodiene insecticide heptachlor at 1/8 and 1/4 LD50 to male and female albino rats before mating affected fertility in both sexes. A decrease in implantations, serum oestrogen and progesterone levels and increase in resorptions in the females was observed. However, no histological changes were observed except for few atretic follicles in the treated females. In males, a dose-dependent significant decrease in the sperm count and coagulating gland fructose levels was observed, with marginal degeneration of seminiferous tubules. These results are indicative of the prenatal toxicity of heptachlor in male and female rats.
 
Date 1995
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
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Identifier http://ir.cftri.com/2258/1/Pharmacology%20%26%20toxicology%2C%20Volume-76%282%20%281995%29%20112-4.pdf
Rani, B. E. A. and Krishnakumari, M. K. (1995) Prenatal toxicity of heptachlor in albino rats. Pharmacology and Toxicology, 76 (2). pp. 112-4. ISSN 0901-9928