Prenatal toxicity of heptachlor in albino rats.
IR@CFTRI: CSIR-Central Food Technological Research Institute, Mysore
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http://ir.cftri.com/2258/
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Title |
Prenatal toxicity of heptachlor in albino rats.
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Creator |
Rani, B. E. A.
Krishnakumari, M. K. |
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Subject |
26 Pesticide Chemistry
17 Toxicology |
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Description |
Exposure of the cyclodiene insecticide heptachlor at 1/8 and 1/4 LD50 to male and female albino rats before mating affected fertility in both sexes. A decrease in implantations, serum oestrogen and progesterone levels and increase in resorptions in the females was observed. However, no histological changes were observed except for few atretic follicles in the treated females. In males, a dose-dependent significant decrease in the sperm count and coagulating gland fructose levels was observed, with marginal degeneration of seminiferous tubules. These results are indicative of the prenatal toxicity of heptachlor in male and female rats.
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Date |
1995
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Type |
Article
PeerReviewed |
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application/pdf
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Language |
en
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—
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Identifier |
http://ir.cftri.com/2258/1/Pharmacology%20%26%20toxicology%2C%20Volume-76%282%20%281995%29%20112-4.pdf
Rani, B. E. A. and Krishnakumari, M. K. (1995) Prenatal toxicity of heptachlor in albino rats. Pharmacology and Toxicology, 76 (2). pp. 112-4. ISSN 0901-9928 |
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