Studies on the Role of Dietary Galectin- Inhibitor on Galectin and Galectin Binding Protein Mediated Metastasis.
IR@CFTRI: CSIR-Central Food Technological Research Institute, Mysore
View Archive Info| Field | Value | |
| Relation |
http://ir.cftri.com/12821/
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| Title |
Studies on the Role of Dietary Galectin-
Inhibitor on Galectin and Galectin
Binding Protein Mediated Metastasis.
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| Creator |
Sindhuja, H. N.
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| Subject |
16 Protein Biochemistry
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| Description |
Metastasis is a crucial step in cancer pathogenicity and adds severity to the
disease mainly because of the entry of cancer cell into a highly manipulative
stage. Several studies including studies from our laboratory have indicated
that galectin-3 plays a key role in metastasis. Galectin-3 binding protein
(G3BP) is reported as a ligand for galectin-3. G3BP is a heavily Nglycosylated
protein with a molecular mass of 90 kDa and it appears to
mediate cell-cell adhesion via bridging galectin-3 molecules on adjacent
tumor cells in a carbohydrate-dependent manner.
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| Date |
2016
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| Type |
Thesis
NonPeerReviewed |
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| Format |
pdf
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| Language |
en
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| Identifier |
http://ir.cftri.com/12821/1/Sindhuja.pdf
Sindhuja, H. N. (2016) Studies on the Role of Dietary Galectin- Inhibitor on Galectin and Galectin Binding Protein Mediated Metastasis. Doctoral thesis, Central Food Technological Research Institute. |
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