Studies on the metabolism of piperine: absorption, tissue distribution and excretion of urinary conjugates in rats.
IR@CFTRI: CSIR-Central Food Technological Research Institute, Mysore
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http://ir.cftri.com/6562/
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| Title |
Studies on the metabolism of piperine: absorption, tissue distribution and excretion of urinary conjugates in rats.
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| Creator |
Bhat, B. G.
Chandrasekhara, N. |
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| Subject |
07 Metabolism
30 Spices/Condiments |
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| Description |
Male albino rats were fed piperine, the major bite factor of black pepper, at a dose of 30 mg (170 mg/kg) by gavage or 15 mg (85 mg/kg) intraperitoneally. About 97% was absorbed irrespective of mode of dosing, 3% was excreted in faeces, but none was detectable in urine. Highest concn. of piperine in the stomach and small intestine was attained at about 6 h. Only traces were detected in serum, kidney and spleen from 30 min to 24 h.
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| Date |
1986
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| Type |
Article
PeerReviewed |
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| Format |
pdf
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| Language |
en
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| Identifier |
http://ir.cftri.com/6562/1/Toxicology%2C%2040%20%281986%29%2083--92.pdf
Bhat, B. G. and Chandrasekhara, N. (1986) Studies on the metabolism of piperine: absorption, tissue distribution and excretion of urinary conjugates in rats. Toxicology, 40 (1). 83-92, 20 ref.. |
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