Liver and erythrocyte L-aspartate: and L-alanine: 2-oxoglutarate aminotransferases of the pyridoxine deficient rat.
IR@CFTRI: CSIR-Central Food Technological Research Institute, Mysore
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http://ir.cftri.com/4570/
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Title |
Liver and erythrocyte L-aspartate: and L-alanine: 2-oxoglutarate aminotransferases of the pyridoxine deficient rat.
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Creator |
Radhakrishnamurthy, R.
Sabry, Z. I. |
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Subject |
07 Enzyme Biochemistry
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Description |
The withdrawal of pyridoxine from the diet of male weading rats did not appear to affect the liver
mitochondrial L-aspartate : 2-oxoglutarate amhotransferase, but the ismnzymes in the liver supematant
and in the erythrocyte showed gradual lowering of activity. The liver kalanine : Zoxoglutarate
aminatransferase activity (mostly residing in the supernatant) showed a sharp and immediate decline,
and that of the erythrocyte exhibited a more gradual decline with the progress of deficiency.
The liver supernatant and erythrocyte aspartate aminotransferases of the deficient animals showed a
marked recowry with subcutaneous injection of pyridoxine and in vitro addition of pyridoxal-5-phosphate
to the enzyme system. The data emphasize the sensitivity of the supernatant and erythrocyte aspartate
aminotransfemses in reflecting the pyridoxine nutritional state of the rat.
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Date |
1968
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Type |
Article
PeerReviewed |
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Format |
pdf
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Language |
en
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Identifier |
http://ir.cftri.com/4570/1/CANADIAN%20JOURNAL%20QF%20BIOCHEMISTRY.%20VOL.%2046%2C%2011968.pdf
Radhakrishnamurthy, R. and Sabry, Z. I. (1968) Liver and erythrocyte L-aspartate: and L-alanine: 2-oxoglutarate aminotransferases of the pyridoxine deficient rat. Canadian Journal of Biochemistry, 46. pp. 1081-1088. |
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