Mammalian toxicity of technical x-factor. I. An acute oral study.
IR@CFTRI: CSIR-Central Food Technological Research Institute, Mysore
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http://ir.cftri.com/4589/
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| Title |
Mammalian toxicity of technical x-factor. I. An acute oral study.
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| Creator |
Krishnakumari, M. K.
Muralidhara, Dr. Muralidhara, S. Majumder, S. K. |
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| Subject |
17 Toxicology
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| Description |
Intragastric administration of acute doses of
Technical X-factor (ß-isomer free BHC, a byproduct
obtained during separation of Lindane from Tech.
BHC) carried in peanut oil elicited typical signs
of central nervous system depression in adult rats.
The computed oral LD5 0 values of X-factor were 4174
and 5673 mg/kg. body weight for male and female
rats respectively indicating that its acute taxicity
was of relatively low order compared to Tech.
BHC. It is suggested that the low acute mammalian
toxicity of X-factor could possibly be due to a direct antagonism of the delta isomer (present in
larger proportion in X-factor) with the gamma isomer.
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| Date |
1982
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| Type |
Article
PeerReviewed |
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| Format |
pdf
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| Language |
en
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| Identifier |
http://ir.cftri.com/4589/1/J.%20ENVIRON.%20SCI.%20HEALTH%2C%20B17%283%29%2C%20241-252%20%281982%29.pdf
Krishnakumari, M. K. and Muralidhara, Dr. and Muralidhara, S. and Majumder, S. K. (1982) Mammalian toxicity of technical x-factor. I. An acute oral study. Journal of Environmental Science and Health, 17B. pp. 241-252. |
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