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Effect of oryzanol on cholesterol absorption & biliary & fecal bile acids in rats.

IR@CFTRI: CSIR-Central Food Technological Research Institute, Mysore

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Title Effect of oryzanol on cholesterol absorption & biliary & fecal bile acids in rats.
 
Creator Seetharamaiah, G. S.
Chandrasekhara, N.
 
Subject 12 Metabolism
19 Lipids-oils/fats
 
Description Effect of oryzanol on biliary secretion of cholesterol, phospholipid and bile acids and fecal excretion of cholesterol and bile acids was examined in male albino rats. Feeding oryzanol at 0.5 per cent level with the control diet did not cause any change in bile flow and composition. On feeding oryzanol with high cholesterol diet, the bile flow and total bile acid output were increased by 12 and 18 per cent respectively, while biliary cholesterol and phospholipids remained unchanged. The increased bile acid secretion was mainly due to taurocholic acid. In rats fed oryzanol along with high cholesterol diet, there was a significant increase in the fecal excretion of cholesterol (28%) and of bile acids (29%), whereas cholesterol absorption was lowered by 20 per cent.
 
Date 1990
 
Type Article
PeerReviewed
 
Format pdf
 
Language en
 
Identifier http://ir.cftri.com/2340/1/IJMR%2092%201990%20471.pdf
Seetharamaiah, G. S. and Chandrasekhara, N. (1990) Effect of oryzanol on cholesterol absorption & biliary & fecal bile acids in rats. The Indian Journal of Medical Research, 92. pp. 471-5. ISSN 0971-5916