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Inhibition of metal catalyzed H2O2 and peroxyl-AAPH mediated protein, DNA and human erythrocytes lipid oxidation using millet phenolics.

IR@CFTRI: CSIR-Central Food Technological Research Institute, Mysore


Field	Value

Relation	http://ir.cftri.com/13576/ https://dx.doi.org/10.1007/s13562-017-0401-2

Title	Inhibition of metal catalyzed H2O2 and peroxyl-AAPH mediated protein, DNA and human erythrocytes lipid oxidation using millet phenolics.

Creator	Palaniswamy, S. K. Vijayalakshmi, G.

Subject	10 Plants 32 Antioxidants

Description	Scientific data on the ability of the millet phenolic profile in prevention of protein and human erythrocyte peroxidation in terms of their cytoprotective properties is scarce. Catechin, ferulic acid and traces of vanillic acid and resveratrol were identified as bound polyphenols. It was determined that all millet varieties bound phenolics prevented DNA oxidation at a lower concentration of 50 lg. At a concentration of 25 lg kodo millet phenolics retained 80% of proteins visualized in SDS-PAGE. Moreover millet phenolics delayed time response for hemolysis and showed an 88.2% inhibition of erythrocyte lipid peroxidation. Though higher antioxidant property was estimated in kodo millet their bioavailability may be affected since much of the polyphenols occurred in bound form or as condensed tannins. Processed kodo millet with increased bioavailable phenolic content would thus be considered effective compared to other millet varieties for its cytoprotective properties.

Date	2017

Type	Article PeerReviewed

Format	pdf

Language	en

Identifier	http://ir.cftri.com/13576/1/J.%20Plant%20Biochem.%20Biotechnol.%20%28October%E2%80%93December%202017%29%2026%284%29406%E2%80%93414.pdf Palaniswamy, S. K. and Vijayalakshmi, G. (2017) Inhibition of metal catalyzed H2O2 and peroxyl-AAPH mediated protein, DNA and human erythrocytes lipid oxidation using millet phenolics. Journal of Plant Biochemistry and Biotechnology, 26 (4). pp. 406-414.