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Radical Scavenging Activity of Decalpoline, A Novel Compound Characterized from Decalepis Hamiltonii

IR@CFTRI: CSIR-Central Food Technological Research Institute, Mysore

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Relation http://ir.cftri.com/10825/
 
Title Radical Scavenging Activity of Decalpoline, A Novel Compound Characterized from Decalepis Hamiltonii
 
Creator Naveen, S.
Aradhya, S. M.
Policegoudra, R. S.
Rao, L. J.
Farhath, K.
 
Subject 06 Trees And Shrubs
32 Antioxidants
 
Description The ethanol extract of Decalepis hamiltonii roots was subjected to antioxidant activity-guided fractionation by repeated silica gel column chromatography to get a pure antioxidant compound which was subjected to extensive analysis by UV, IR, LC-MS, and 2D HMQC NMR. The spectral data of the isolated compound was analyzed, and its structure was elucidated as decalpoline, a novel antioxidant compound not reported so far. Decalpoline exhibited multiple antioxidant properties like DPPH scavenging activity, superoxide radical scavenging activity, lipid peroxidation inhibitory activity, metal chelating and total reducing activity.
 
Date 2012
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Identifier http://ir.cftri.com/10825/1/Chemistry%20of%20Natural%20Compounds%2C%202012%2C%20Volume%2048%2C%20Number%202%2C%20Pages%20225-230.pdf
Naveen, S. and Aradhya, S. M. and Policegoudra, R. S. and Rao, L. J. and Farhath, K. (2012) Radical Scavenging Activity of Decalpoline, A Novel Compound Characterized from Decalepis Hamiltonii. Chemistry of Natural Compounds, 48 (2). pp. 225-230.